Effects of 12 weeks of inspiratory muscle training and whole body vibration on the inflammatory profile, BDNF and muscular system in pre-frail elderly women: A randomized controlled trial.

AIM: to investigate the effects of the whole body vibration (WBV) and inspiratory muscle training (IMT) on the inflammatory profile and in muscle mass and strength in pre-frail older women. METHODS: this study was a randomized double-blind trial. Forty two older women aged 60-80 years were randomly allocated to IMT + WBV (G1), IMTsham + WBV (G2) or Sham groups (G3). During 12 weeks G1 received both trainings, whereas G2 received WBV alone and G3 received IMT with a low fixed load and were positioned at the vibratory platform without therapeutic effect. Participants were evaluated before and after the intervention for the following outcomes: Brain-derived neurotrophic factor (BDNF) and inflammatory biomarkers (IB), respiratory (RT) and quadriceps thickness (QT) and diaphragmatic mobility (DM) using muscle ultrasound, body composition (BC) using a bioelectrical impedance scale and inspiratory muscle strength (IMS). RESULTS: after the training, G1 (114.93 ± 21.29) improved IMS (p<0.005) compared with G2 (91.29 ± 23.10) and G3 (85.21 ± 27.02). There was also a significant improve on time of the DM (p<0.001) and RT (p=0.006) for G1 (8.59 ± 3.55 and 11.11 ± 12.66) compared with G2 (1.05 ± 3.09 and 1.10 ± 10.60) and G3 (0.40 ± 2.29 and -1.85 ± 7.45). BDNF, IB, QT and BC were similar between groups. CONCLUSIONS: IMT associated with WBV is effective to improve in increasing IMS, RT and DM in pre-frail older women. However, these interventions do not modify BDNF, IB, QT or BC in this population.

Inspiratory muscle training in addition to whole body vibration for functional and physical outcomes in pre-frail older women: a randomized controlled trial.

BACKGROUND: to investigate the efficacy of addition of inspiratory muscle training (IMT) to the whole body vibration (WBV) on functional outcomes, physical performance, muscle strength and metabolism in pre-frail older women. METHODS: this study was a randomized double-blind trial. Forty-two older women aged 60-80 years who meet the Cardiovascular Health Study frailty criteria for pre-frailty were randomly allocated to IMT + WBV, IMTsham + WBV or Sham groups. IMT + WBV group received 12 weeks of both trainings, whereas IMTsham + WVB received 12 weeks of WBV alone. Sham group received 12 weeks of IMT with a low fixed load and were positioned at the vibratory platform without therapeutic effect. Participants were evaluated before and after the intervention for the following outcomes: 6-min walk test distance (6MWD), balance using Tinetti test, functional mobility using timed up and go test (TUG), handgrip strength (HGS) and peripheral muscle metabolism (glucose and lactate levels). RESULTS: after the training, both groups IMT + WBV and IMTsham + WBV improved 6MWD [mean percentage changes = 20.31 (SD = 14.62) and 13.02 (SD = 12.14), respectively] compared with Sham [0.27 (SD = 6.51)], P <0.01. There was also a significant decrease of mean percentage changes on time of the TUG for IMT + WBV [-21.87 (SD = 7.87)] and IMTsham + WBV [-11.15 (SD = 13.64)] compared with Sham [-4.25 (SD = 13.25)], P <0.01. IMT + WBV group improved balance when compared with IMTsham + WBV and Sham groups (P <0.05 and < 0.01, respectively). HGS and levels of lactate and glucose were similar between groups. CONCLUSIONS: the addition of IMT to the WBV was effective to improve functionality, balance and physical performance in pre-frail older women.

Acute Whole Body Vibration Decreases the Glucose Levels in Elderly Diabetic Women.

Type II diabetes (TIIDM) is characterized by high levels of blood glucose followed by excessive insulin release so that the target cells become less sensitive, developing insulin resistance and maintaining hyperglycemic levels. Physical activity is the strongest element to prevent and to manage the TIIDM, and the majority of patients do not remain in regularly active levels, because the premature fatigue in these patients decreases the adherence to the training. Contrastingly, the whole body vibration (WBV) training may improve the glucose metabolism in diabetic patients, reducing the peripheral blood sugar, decreasing the physical discomfort and perceived exertion. Therefore, the purpose of the study was to determine the effect of an acute WBV session as therapy to promote fasting decreases in insulin levels in peripheral blood in TIIDM when compared to healthy elderly. For this, fifteen healthy elderly women and fourteen diabetic elderly women, all sedentary, were allocated in diabetic or control groups, and we made an acute whole body session composed of 10 bouts lasting 2 minutes each one, separated by a 30-second rest period. The WBV was executed in a triaxial platform MY3 Power Plate® at 35 hertz and has been chosen a peak-to-peak displacement of 4 millimeters. After the protocol, both groups decreased the glycemic levels and increased lactate production in relation to the basal levels and when compared diabetic and control, where the most important results have been shown in diabetic women. This study revealed that WBV training in TIIDM has had significant beneficial effects on the control of glucose levels, still in an acute session. So that, the complete training probably will show better results about glycemic control and this finding could be especially important when prescribing exercise for elderly who are unable or unwilling to use traditional loads or who show poor exercise compliance.

Immediate effects of respiratory muscle stretching on chest wall kinematics and electromyography in COPD patients.

This study evaluated the immediate effects of respiratory muscle stretching on chest wall kinematics and electromyographic activity in COPD patients. 28 patients with COPD were randomized into two groups: 14 to the treatment group (TG) and 14 to the control group (CG). The TG underwent a stretching protocol of the rib cage muscles, while the CG remained at rest under similar conditions. After a single session, TG increased the tidal volume of the pulmonary rib cage (Vrcp) (p=0.020) and tidal volume of abdominal rib cage (Vrca) (p=0.043) variations and their percentages in relation to the thoracic wall, Vrcp% (p=0.044) and Vrca% (p=0.022). Also, TG decreased the end-expiratory Vrcp (p=0.013) and the end-inspiratory Vrcp (p=0.011) variations. In addition, there was a reduction in respiratory rate (RR) (p=0.011) and minute volume (MV) (p=0.035), as well as an increase in expiratory time (Te) (p=0.026). There was also an immediate reduction in sternocleidomastoid (p=0.043) and upper trapezium (p=0.034) muscle electrical activity. Then, the study supports the use of stretching to improve COPD chest wall mobility with positive effects on chest wall mechanics, on volume distribution and electromyography.

Vibrating Platform Training Improves Respiratory Muscle Strength, Quality of Life, and Inspiratory Capacity in the Elderly Adults: A Randomized Controlled Trial.

BACKGROUND: Aging affects respiratory strength that could cause reduction in functional capacity and quality of life, playing a fundamental role in healthy aging and survival. To prevent these declines, the whole body vibration (WBV) has been proposed to increase strength and functional capacity. The aim of the study was to evaluate the effects of WBV on respiratory muscle strength, thoracoabdominal ventilation, and quality of life in the elderly adults. METHODS: This study was a controlled, randomized double-blind clinical trial. The study included 28 elderly adults randomized into three groups: Resistance (n = 9), WBV (n = 9), or WBV + resistance exercises (n = 10), performing training, sham, or double training for 3 months, twice per week. The variables of the study were as follows: maximal inspiratory and expiratory pressures (MIP and MEP), distribution of thoracoabdominal volumes variation in optoelectronic plethysmography (pulmonary rib cage-VRCp, abdominal rib cage-VRCa, and abdomen-VAB), and quality of life. RESULTS: After training, WBV and WBV + resistance groups increased MIP and MEP (p < .001). During inspiratory capacity maneuver, WBV groups had incremental increases in chest wall total volume (p < .001), showing a rise in pulmonary rib cage (p = .03) and abdominal rib cage (p = .04). Furthermore, WBV groups improved SF-36 scores in functional capacity, physical aspects, energy, pain, and general heath domains. CONCLUSIONS: The WBV is a training that could improve respiratory muscle strength and quality of life and promote different ventilatory strategies in chest wall and thoracoabdominal compartments in healthy elderly adults.

Effects of Whole Body Vibration on Muscle Strength and Quality of Life in Health Elderly: A Meta-Analysis / Efeitos da Vibração de Corpo Inteiro na Força Muscular e Qualidade de Vida em Idosos Saudáveis: Uma Meta-análise

Abstract Introduction: The literature presents different findings about the vibration training efficacy on muscle per- formance, even using protocols with similar parameters. Objective: The purpose of this systematic review was to investigate the effects of whole body vibration (WBV) on strength and quality of life in health elderly people, presenting a meta-analisys. Methods: PubMed, CINAHL, SciELO, LILACS and PEDro databases were systematically searched for studies that used WBV in healthy elderly. These searches were supplemented with material identified in references and a qualitative and quantitative analysis was performed to sum- marize the findings. The search was performed by two independent researchers with a third was selected to solve problems of search disagreement, data collection, and quality score. Results: Nine studies with strength outcome and two studies with quality of life outcome were identified, with sample ranging 21 to 220 elderly, all studies had control groups performing exercises or guidelines. Some studies have shown sig- nificant improvements in muscle strength, muscle power, vertical jump height, timed get up and go test and quality of life. Conclusion: The meta-analysis of the findings in these studies shows that WBV could benefit health elderly, increasing muscle strength and improving the quality of life mainly in functional capacity. The number of publications found in the databanks searched is small, with limitations in design of protocols with a weakness to the interpretation of the findings, suggesting the need of investigation with WBV with well-designed protocols and controlled parameters into the effects of WBV training in elderly people.

Resumo Introdução: A literatura apresenta diferentes resultados sobre a eficácia do treinamento da vibração de corpo inteiro sobre o desempenho muscular, mesmo utilizando protocolos com parâmetros semelhantes. Objetivo: O objetivo desta revisão sistemática foi investigar os efeitos da vibração de corpo inteiro (VCI) sobre a força e a qualidade de vida em idosos saudáveis, apresentando uma meta-análise. Métodos: A busca ocorreu nas bases de dados PubMed, CINAHL, SciELO, Lilacs e Pedro visando estudos sobre o uso de WBV em idosos saudáveis. Essas pesquisas foram complementadas com material identificado nas referências e foi realizada uma análise quali-quantitativa resumindo os resultados. A pesquisa foi realizada por dois pesquisadores independentes, com um terceiro sendo selecionado para resolver problemas de desacordo na busca, coleta de dados e índice de qualidade. Resultados: Foram identificados nove estudos com desfecho força e dois estudos com desfechos na qualidade de vida, com amostras entre 21-220 idosos, todos com grupo controle recebendo orientações ou realizando outro tipo de exercício. Alguns estudos mostraram melhorias significativas da força e desempenho musculares, da altura do salto vertical, do teste Timed Up and Go e da qualidade de vida. Conclusão: A meta-análise dos resultados destes estudos indicam que VCI pode beneficiar idosos saudáveis, aumentando a força muscular e melhorando a qualidade de vida, principalmente na capacidade funcional. O número de publica- ções encontradas nas bases de dados pesquisadas foi pequeno, com limitações na concepção de protocolos com uma fragilidade na interpretação dos achados, sugerindo a necessidade de investigação da VCI com protocolos melhor desenhados e com parâmetros controlados na WBV em idosos.

Posicionamento corporal alterando a força muscular respiratória e o grau de obstrução em crianças asmáticas / Changes in postural position altering the respiratory muscle strength and level of obstruction in asthmatic children

INTRODUÇÃO: A asma é uma desordem inflamatória crônica que, em casos graves, altera o fluxo aéreo, mesmo no período intercrise. OBJETIVO: Verificar, em crianças asmáticas, a influência das posturas sentada ereta e sentada inclinada para frente sobre o efeito da nebulização medicamentosa, avaliando as forças inspiratória e expiratória máximas (PI máx e PE máx) e o pico de fluxo expiratório (PFE). MÉTODO: 57 crianças, na faixa etária de 6 a 12 anos, foram distribuídas em três grupos: Grupo I, com crianças na postura sentada ereta e sentada inclinada para frente; Grupo II, com crianças na postura sentada ereta antes e após a nebulização; e Grupo III, com crianças na postura sentada inclinada para frente antes e após a nebulização. As crianças foram avaliadas três vezes nas medidas analisadas. Para comparação, foi utilizado o teste t de student (pareado) RESULTADOS: A PI máx, a PE máx e o PFE foram maiores na posição sentada inclinada para frente, com p = 0,003, p = 0,006 e p = 0,000, respectivamente. Após a nebulização, o Grupo II apresentou aumentos de 44,16% na PI máx, 36,02% no PEF e 34,88% na PE máx. Após a nebulização, o Grupo III apresentou elevação de 69,46% na PI máx, 60,87% na PE máx e 52,05% no PFE. Comparados os grupos II e III, os ganhos são maiores no Grupo III, com (p < 0,05) para as medidas do PFE e da PE máx. CONCLUSÃO: A postura sentada inclinada para frente oferece maior vantagem mecânica para a musculatura expiratória, favorecendo a redução da obstrução, por evidenciar aumentos na PE máx e no PFE.

INTRODUCTION: Asthma is a chronic inflammatory disorder which in severe cases changes the air flow, even in the period between episodes. OBJECTIVE: To evaluate, in asthmatic children under the effect of nebulized drug, the influence of upright sitting and leaning forward sitting postures, by assessing the intensity of the inspiratory and expiratory pressures (MIP and MEP) and peak expiratory flow (PEF). METHODS: 57 children aged 6-12 years were divided in three groups: In Group I, both postures, upright sitting and leaning forward sitting, were assessed without using nebulized drug; in Group II, only the upright sitting posture was assessed before and after nebulization; in Group III, only the leaning forward sitting posture was assessed before and after nebulization. The measures were repeated by assessing these children three times in a single session. A student t-test (pared) was used for comparisons. RESULTS: MIP, MEP and PEF were higher in the leaning forward position indicating respective p values of p = 0.003, p = 0.006 and p = 0.000. After nebulization, the Group II demonstrated an increase of 44.16% in MIP, 36.02% in PEF and 34.88% in MEP. After nebulization, the Group III showed a gain of 69.46% in MIP, 60.87 in MEP and 52.05% in PEF. The difference between groups II and III were significant (p < 0.05) for levels of PEF and MEP, indicating that the Group III showed better performance during these tests. CONCLUSION: It can be suggested that the leaning forward sitting posture provided an increased mechanical advantage for expiratory muscles, favoring the airflow during expiration and reducing the obstruction as evidenced by MEP and PEF increase.